01 - Preheat oven to 400°F and line a baking sheet with parchment paper.
02 - In a large mixing bowl, blend ground beef, egg, breadcrumbs, Parmesan cheese, garlic, parsley, salt, black pepper, and red pepper flakes if used, mixing until just incorporated without overworking.
03 - Shape the mixture into 1-inch diameter balls and arrange them on the prepared baking sheet.
04 - Bake meatballs for 15 minutes until browned and fully cooked.
05 - While meatballs bake, combine tomato sauce, olive oil, honey or brown sugar, Worcestershire sauce, oregano, and garlic powder in a saucepan over medium heat; simmer for 5 minutes, stirring occasionally.
06 - Transfer baked meatballs into the saucepan, gently toss to coat, and simmer together for 3 to 5 minutes to meld flavors.
07 - Serve warm, optionally garnished with additional parsley and accompanied by toothpicks for easy handling.